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Pk/pd evaluation of protein binding of ceftriaxone and levofloxacin in seriously ill patients

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: SCOULAR, Sarah (University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Clinical Pharmacy)
  • Co-author(s): Sarah Scoular: Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, United States
    Ashley Hall
    Sanjana Rao: University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, ;, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, United States
    Scott Mueller: Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, United States
    Ty Kiser: Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, United States
    Doug Fish: Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, United States
  • Abstract:

    Background

    Protein deficiency in seriously ill patients may lead to increased unbound serum concentrations of highly protein bound antibiotics potentially leading to improved clinical outcomes.

    Methods

    Patients ≥18 years of age with creatinine clearance ≥50 ml/minute were prospectively enrolled into PK studies of ceftriaxone (CRO) and levofloxacin

    ..

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Last update 4 October 2019

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