Effect of BAPTA-AM on hydrogen peroxide-induced cell hypertrophy in H9c2 cardiomyblasts

• In: Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: CBS-P-02
• By: SAKURAI, Koichi (Hokkaido Pharmaceutical University School of Pharmacy, Life Science, Otaru, Japan)
• Co-author(s): Oyama, K. (Hokkaido Pharmaceutical University School of Pharmacy, Otaru, Japan)
  
• Abstract:

  Cardiomyocyte hypertrophy induced by various stress such as pressure overload, ischemia/reperfusion and oxidative stress leads to serious arrhythmia and cardiac failure. It is demonstrated that intracellular calcium [Ca² ]_i level is increased in the process of hypertrophy. Although several calcium chelators prevent the hypertrophy in vitro, its

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