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Both passive lipoidal diffusion and carrier-mediated uptake are important transport mechanisms in drug disposition

  • At: 2014 FIP Congress in PSWC, Melbourne (Australia)
  • Type: Presentation
  • By: AVDEEF, Alex (In-ADME Research, New york city, United States of America)
  • Abstract:

    The disposition of pharmaceuticals in the various organs of the body depends on the movement of drugs across cellular membranes. Recently, Kell and coworkers1-5 put forward a controversial hypothesis that carrier-mediated transport accounts for all the cellular uptake of pharmaceuticals, and that passive lipoidal diffusion of drugs across..

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Last update 4 October 2019

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