Both passive lipoidal diffusion and carrier-mediated uptake are important transport mechanisms in drug disposition
- At: 2014 FIP Congress in PSWC, Melbourne (Australia)
- Type: Presentation
- By: AVDEEF, Alex (In-ADME Research, New york city, United States of America)
The disposition of pharmaceuticals in the various organs of the body depends on the movement of drugs across cellular membranes. Recently, Kell and coworkers1-5 put forward a controversial hypothesis that carrier-mediated transport accounts for all the cellular uptake of pharmaceuticals, and that passive lipoidal diffusion of drugs across.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.