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Comparative in vitro dissolution studies of commercial diclofenac suppositories using the rotating dialysis cell and the flow through methods.

  • At: Amsterdam (the Netherlands) (2012)
  • Type: Poster
  • By: YOMOTA, Chikako (National Institute of Health Sciences, Drug Division, Tokyo, Japan)
  • Co-author(s): Hotate, H. (National Institute of Health Sciences, Tokyo, Japan)
    Izutsu, K. (National Institute of Health Sciences, Tokyo, Japan)
    Okuda, H. (National Institute of Health Sciences, Tokyo, Japan)
  • Abstract:


    : Several reports described that some diclofenac sodium suppositories are less effective than the innovator product. At the present time there are 8 commercially available generic poroducts in Japan.

    : In order to compare their quality, in vitro release tests were investigated at several temperatures and the release profiles were


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Last update 4 October 2019

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