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Structure-based virtual screening, synthesis and biological evaluation of novel anti-toxoplasma and anti-neospora agents

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: LABOUTA, Ibrahim (University of Alexandria, Pharmaceutical Chemistry, Alexandria, Egypt)
  • Co-author(s): El-Semary, M.M. (University of Alexandria, Alexandria, Egypt)
    Saudi, M.N. (University of Alexandria, Alexandria, Egypt)
    Badr, M.H. (University of Alexandria, Alexandria, Egypt)
    Abdelkader, E.H. (University of Alexandria, Alexandria, Egypt)
  • Abstract:

    Toxoplasmosis is a worldwide parasitic disease caused by
    Toxoplasma gondii

    infecting between 30-65% of the human population which causes life-threatening complications in children and immunocompromised patients. In this work, we report a structure-based virtual screening (VS) study targeting
    Toxoplasma gondii

    Dihydrofolate reductase. Through two

    ..

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Last update 4 October 2019

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