Enhanced bioavialability and sustained release of diclofenac from a swellable hydrogel
- At: 2004 FIP Congress in New Orleans (USA)
- Type: Poster
- By: RAJKAMAL, Bigala Big (J.S.S. College of Pharmacy, Department of Pharmaceutical Chemistry, Ootacamund, Tamilnadu State, India)
- Co-author(s): Ravichandran (University of South Pacific, United States of America)
Chandrasekhar (J.S.S. College of Pharmacy, OOTACAMUND, TAMILNADU STATE, India)
Nanjan (J.S.S. College of Pharmacy, OOTACAMUND, TAMILNADU STATE, India)
Suresh (J.S.S. College of Pharmacy, OOTACAMUND, TAMILNADU STATE, India)
A polymeric pro-drug of Diclofenac was synthesised and its in vitro drug release behavior was carried out at two different pH mimicking the upper and lower GI tract. bioavailability investigations show complete drug absorption from the polymeric pro-drug.
Several approaches have been made in the past to overcome the GI.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.