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Additive anticonvulsant effects of agmatine and lithium chloride on pentylenetetrazole-induced clonic seizure in mice: involvement of a2-adrenoceptor

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: EBRAHIMI, Ali (Tehran University of Medical Sciences, Students’ scientific research center, Tehran, Iran)
  • Co-author(s): Payandemehr, B. (Tehran University of Medical Sciences, Tehran, Iran)
    Bahremand, A. (Tehran University of Medical Sciences, School of Medicine, Department of Pharmac, Tehran, Iran)
    Ziai, P. (Tehran University of Medical Sciences, School of Medicine, Department of Pharmac, Tehran, Iran)
    Rahimian, R. (Tehran University of Medical Sciences, School of Medicine, Department of Pharmac, Tehran, Iran)
    Khezrian, M. (Tehran University of Medical Sciences, School of Medicine, Department of Pharmac, Tehran, Iran)
    Ghasemi, M. (Tehran University of Medical Sciences, School of Medicine, Department of Pharmac, Tehran, Iran)
    Montaser-Kouhsari, L. (Tehran University of Medical Sciences, School of Medicine, Department of Pharmac, Tehran, Iran)
    Dehpour, A.R. (Tehran University of Medical Sciences, School of Medicine, Department of Pharmac, Tehran, Iran)
    Ghasemi, A. (Tehran University of Medical Sciences, School of Medicine, Department of Pharmac, Tehran, Iran)
  • Abstract:

    After 60 years, lithium is still the mainstay in the treatment of mood disorders and widely used in clinic. In addition to its mood stabilizer effects, lithium also shows some anticonvulsant properties. Similar to lithium, agmatine also plays a protective role in the CNS against seizures and has been reported to enhance the effect of different

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Last update 4 October 2019

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