Effect of BAPTA-AM on hydrogen peroxide-induced cell hypertrophy in H9c2 cardiomyblasts
- At: 2012 FIP Congress in Amsterdam (the Netherlands)
- Type: Poster
- By: SAKURAI, Koichi (Hokkaido Pharmaceutical University School of Pharmacy, Life Science, Otaru, Japan)
- Co-author(s): Oyama, K. (Hokkaido Pharmaceutical University School of Pharmacy, Otaru, Japan)
Cardiomyocyte hypertrophy induced by various stress such as pressure overload, ischemia/reperfusion and oxidative stress leads to serious arrhythmia and cardiac failure. It is demonstrated that intracellular calcium [Ca2 ]i level is increased in the process of hypertrophy. Although several calcium chelators prevent the hypertrophy in vitro, its.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.