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Effect of BAPTA-AM on hydrogen peroxide-induced cell hypertrophy in H9c2 cardiomyblasts

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: SAKURAI, Koichi (Hokkaido Pharmaceutical University School of Pharmacy, Life Science, Otaru, Japan)
  • Co-author(s): Oyama, K. (Hokkaido Pharmaceutical University School of Pharmacy, Otaru, Japan)
  • Abstract:

    Cardiomyocyte hypertrophy induced by various stress such as pressure overload, ischemia/reperfusion and oxidative stress leads to serious arrhythmia and cardiac failure. It is demonstrated that intracellular calcium [Ca2 ]level is increased in the process of hypertrophy. Although several calcium chelators prevent the hypertrophy in vitro, its


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Last update 4 October 2019

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