Effect of cytochrome P450 1A2 genotype on theophylline pharmacokinetics and its interaction with decursinol angelate
- At: 2012 FIP Congress in Amsterdam (the Netherlands)
- Type: Poster
- By: CHAE, Jung-Woo (College of pharmacy, Daejeon, South-Korea)
- Co-author(s): Hwang, S.Y. (Chungnam National University, Daejeon, South-Korea)
Kwon, K.I. (Chungnam National University, Daejeon, South-Korea)
I. BackgroundHerb–drug interactions represent a serious problem as herbal medicine is used extensively in the modern world.II. AimsThis study investigated the effects of decursinol angelate on the pharmacokinetics of theophylline, a typical substrate of the cytochrome P450 1A2 enzyme, in rats.III. MethodsAfter 3 days of decursinol angelate.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.