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Effect of cytochrome P450 1A2 genotype on theophylline pharmacokinetics and its interaction with decursinol angelate

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: CHAE, Jung-Woo (College of pharmacy, Daejeon, South-Korea)
  • Co-author(s): Hwang, S.Y. (Chungnam National University, Daejeon, South-Korea)
    Kwon, K.I. (Chungnam National University, Daejeon, South-Korea)
  • Abstract:

    I. BackgroundHerb–drug interactions represent a serious problem as herbal medicine is used extensively in the modern world.II. AimsThis study investigated the effects of decursinol angelate on the pharmacokinetics of theophylline, a typical substrate of the cytochrome P450 1A2 enzyme, in rats.III. MethodsAfter 3 days of decursinol angelate


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Last update 4 October 2019

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