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Analysis of Effects of Lubricant level, mixing time and tableting speed on dissolution of Glimpiride tablets

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: PAšIC-KULENOVIC, Maja (Bosnalijek, Development Department, Sarajevo, Bosnia and Herzegovina)
  • Co-author(s): Mekinjic, V. (Bosnalijek, Sarajevo, Bosnia and Herzegovina)
    Alagic-Džambic, L. (Bosnalijek, Sarajevo, Bosnia and Herzegovina)
    Trobradovic, H. (Bosnalijek, Sarajevo, Bosnia and Herzegovina)
    Vehabovic, M. (Bosnalijek, Sarajevo, Bosnia and Herzegovina)
  • Abstract:

    BACKGROUND
    Glimepiride is one of the third generation sulfonylureas used for treatment of type 2 diabetes. With material such as lactose, friction resistance during compression and ejection can be considerable, and it may be impossible to remove the tablet from the die. The presence of lubricant coating may cause an increase in the disintegration

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Last update 4 October 2019

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