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Effect of chitosan molecular weight on drug release from directly compressed alginate-chitosan matrices

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: CALIJA, Bojan (Faculty of Pharmacy, University of Belgrade, Department of Pharmaceutical Technology and Cosmetology, Belgrade, Serbia)
  • Co-author(s): Djuris, J. (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
    Cekic, N. (Faculty of Tecnhology, University of Nis, Leskovac, Serbia)
    Radulovic, Z. (R&D Institute, Galenika, Belgrade, Serbia)
    Milic, J. (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
  • Abstract:


    Aims

    . The aim of the presented work was to evaluate the effect of sodium alginate (SA)/chitosan (CH) ratio and CH molecular weight on drug release and swelling kinetics of SA-CH directly compressed matrices.
    Methods

    . Matrices containing 200 mg of naproxen were prepared by direct compression of mixtures of the drug, SA and one of the following types

    ..

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Last update 4 October 2019

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