Menu
  • Join
  • Login
  • Contact
 

Search abstracts


The new pH sensitive polycation improves the transfection activity of R8-modified lipid nanoparticles by facilitating siRNA condensation

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: TORIYABE, Naoyuki (Hokkaido University, Faculty of Pharmaceutical Science, Sapporo, Japan)
  • Co-author(s): Hayashio, Y. (Hokkaido University, Sapporo, Japan)
    Akita, H. (Hokkaido University, Sapporo, Japan)
    Harashima, H. (Hokkaido University, Sapporo, Japan)
  • Abstract:


    ?. Background

    We previously developed octaarginine (R8) and GALA, as a pH-sensitive fusogenic peptide modified a lipid Double-lamellar Multifunctional Envelope-type Nanoparticles Device (R8/GALA-D-MEND) for siRNA delivery. Herein, we report whether a new pH sensitive polycation (pHSP), as a siRNA condensed polycation in response to pH difference,

    ..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 4 October 2019

FIP Congresses