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Improved dissolution and permeability of exemestane using gelucire 50/13

  • At: 2012 FIP Congress in Amsterdam (the Netherlands)
  • Type: Poster
  • By: ALI, Munawar (St. Peter's Institute of Pharmaceutical Sciences, Pharmaceutics, Warangal, India)
  • Co-author(s): Eedara, B.B. (St Peter's Institute of Pharmaceutical Sciences, Warangal, India)
    Kankane, M. (St Peter's Institute of Pharmaceutical Sciences, Warangal, India)
    Bandari, S. (St Peter's Institute of Pharmaceutical Sciences, Warangal, India)
  • Abstract:

    The purpose of the work was to increase the dissolution rate and permeability of Exemestane by preparing solid dispersions with Gelucire 50/13. The aqueous solubility of the drug was found to be 80µg/ml. The solubility of the drug was increased with increasing concentrations of Gelucire 50/13 indicating Atype solubility phase diagram. Solid

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Last update 4 October 2019

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