High content screening of 3D cell cultures for novel breast cancer therapy combinations
- At: 2012 FIP Congress in Amsterdam (the Netherlands)
- Type: Poster
- By: TORASKAR, Jimita (Leiden/Amsterdam Centre for Drug Research, Leiden University, Leiden, The Nether, Toxicology, Leiden, Netherlands)
- Co-author(s): Price, L.S. (Leiden/Amsterdam Centre for Drug Research, Leiden, Netherlands)
A 3D cell culture model has been developed to screen for novel therapeutic combinations to treat particularly aggressive types of invasive breast cancer. Under 2D cell culture, cells have disrupted expression profile of metabolic enzymes and drug transporters and other proteins that are relevant to the disease profile and drug responsiveness,.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.