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In vitro and in vivo studies on rectal suppositories containing acemetacin

  • In: SIG Bioavailability / Bioequivalence - Poster Session
  • At: Cairo (Egypt) (2005)
  • Type: Poster
  • Poster code: BB-P-007
  • By: BERGISADI, Nazan (Istanbul university, Pharmaceutical Technology, Istanbul, Turkey)
  • Co-author(s): Kabasakal (Marmara University, ISTANBUL, Turkey)
    Uzunkaya (Istanbul university, ISTANBUL, Turkey)
    Gungor (Istanbul university, ISTANBUL, Turkey)
    Yurdun (Marmara University, ISTANBUL, Turkey)
    Keyer Uysal (Marmara University, ISTANBUL, Turkey)
  • Abstract:

    Acemetacin, a non-steroidal anti-inflammatory drug with analgesic and anti-inflammatory properties, is glycolic acid ester of indomethacin. Metabolic studies of acemetacin suggest that the drug is rapidly absorbed orally and hydrolized by the liver to produce indomethacin as its major active metabolite. Currently acemetacin is used orally for the..

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Last update 28 September 2023

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