Release characterization and in vivo bioavailability of acetaminophen dosage forms

• In: Industrial Pharmacy Posters
• At: Hyderabad (India) (2011)
• Type: Poster
• Poster code: IPS-P-18
• By: LEE, Beom-Jin (Kangwon National University, Chuncheon, South-Korea)
• Co-author(s): Park, Jun Bom (Kangwon National University, Chuncheon, South-Korea)
  Choi, Yun-Woong (Korea United Pharm., Ltd,, Seoul, South-Korea)
  Tran, Phuong (Kangwon National University, Chuncheon, South-Korea)
  Tran, Thao (Kangwon National University, Chuncheon, South-Korea)
  Cao, Qing-Ri (SooChow University, Soochow, China)
  Choung, Se-Young (Kyunghee University, Seoul, South-Korea)
  Cheong, Jae-Hoon (Sahm Yook University, Seoul, South-Korea)
  
• Abstract:

  Three different monolithic hydroxypropylmethylcellulose (HPMC) matrix tablets containing 650 mg acetaminophen with immediate release (M-IR), extended release (M-ER), and dual release as their combined release forms (M-IR/ER) were prepared. Then, release mechanism, swelling properties and in vivo bioavailability were compared with commercial..

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