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Rapid and sensitive HPLC-MS/MS method for measuring ribavirin and its application in human pharmacokinetics

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Poster
  • By: YANG, MIN (Research Center of Medical Science, Guangdong Provincial People's Hospital, Guangzhou, China)
  • Co-author(s): ZHOU, Zhi-Ling (Research Center of Medical Science, Guangdong Provincial People's Hospital, GUANGZHOU, China)
    YU, Xi-Yong (Research Center of Medical Science, Guangdong Provincial People's Hospital, GUANGZHOU, China)
    CHEN, Tie-Feng (Research Center of Medical Science, Guangdong Provincial People's Hospital, GUANGZHOU, China)
    LIN, Qiu-Xiong (Research Center of Medical Science, Guangdong Provincial People's Hospital, GUANGZHOU, China)
    SHAN, Zhi-Xin (Research Center of Medical Science, Guangdong Provincial People's Hospital, GUANGZHOU, China)
    LIU, Xiao-Ying (Research Center of Medical Science, Guangdong Provincial People's Hospital, GUANGZHOU, China)
    DENG, Chun-Yu (Research Center of Medical Science, Guangdong Provincial People's Hospital, GUANGZHOU, China)
    HUANG, Xiao-Zhong (Research Center of Medical Science, Guangdong Provincial People's Hospital, GUANGZHOU, China)
    LIN, Shu-Guang (Research Center of Medical Science, Guangdong Provincial People's Hospital, GUANGZHOU, China)
  • Abstract:

    Ribavirin is a synthetic purine nucleoside analog with a broad spectrum of antiviral activity. There are no detailed pharmacokinetic data have been reported for this drug in Chinese until now, it is necessary to assess ribavirin pharmacokinetics in Chinese and develop a rapid and sensitive method for the measurement of ribavirin in human plasma.

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Last update 4 October 2019

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