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Drug interaction associated with kampo medicine; inhibition of abc transporter-mediated transport by herb extracts and terpenoids in the intestinal absorption process

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Poster
  • By: YOSHIDA, Naoko (Department of Hospital Pharmacy, Hamamatsu University School of Medicine, Hamamatsu, Japan)
  • Co-author(s): Kawakami, Junichi (Department of Hospital Pharmacy, Hamamatsu University School of Medicine, HAMAMATSU, Japan)
    Takada, Tappei (Department of Pharmacy, University of Tokyo Hospital, The Univ. Tokyo, Tokyo, Japan)
    Suzuki, Hiroshi (Department of Pharmacy, University of Tokyo Hospital, The Univ. Tokyo, Tokyo, Japan)
    Adachi, Isao (Department of Pharmacy, Toyama University Hospital, University of Toyama, Japan)
  • Abstract:

    The possibility of interactions between natural products/supplements and conventional prescription medicines is one of the most important issues in pharmacotherapeutic safety. Recently, we reported that some terpenoids such as (R)-(+)-citronellal and glycyrrhetic acid, which are present in herbal medicines, can act as inhibitors of P-glycoprotein..

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Last update 4 October 2019

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