Topical delivery of 5-ala from cataionic ultradeformable liposome

• In: SIG: Pharmaceutical Biotechnology - Posters
• At: Basel (Switzerland) (2008)
• Type: Poster
• Poster code: PB-P-012
• By: KIM, Chong-Kook (Seoul National University, Seoul, South-Korea)
• Co-author(s): Oh, Eun-Kyung (Seoul National University, SEOUL, South-Korea)
  Go, An-Na (Seoul National University, SEOUL, South-Korea)
  Ban, Eunmi (Seoul National University, SEOUL, South-Korea)
  
• Abstract:

  In photodynamic therapy (PDT), 5-Aminolevulinic acid (5-ALA) applied topically is converted into protoporphyrin (PpIX), a photosensitizing agent, which is activated by light to induce cell death through free radical formation. However, 5-ALA has limited penetration into the skin due to its hydrophilic, zwiterionic characteristics. In the present..

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