Topical delivery of 5-ala from cataionic ultradeformable liposome
- At: 2008 FIP Congress in Basel (Switzerland)
- Type: Poster
- By: KIM, Chong-Kook (Seoul National University, Seoul, South-Korea)
- Co-author(s): Oh, Eun-Kyung (Seoul National University, SEOUL, South-Korea)
Go, An-Na (Seoul National University, SEOUL, South-Korea)
Ban, Eunmi (Seoul National University, SEOUL, South-Korea)
In photodynamic therapy (PDT), 5-Aminolevulinic acid (5-ALA) applied topically is converted into protoporphyrin (PpIX), a photosensitizing agent, which is activated by light to induce cell death through free radical formation. However, 5-ALA has limited penetration into the skin due to its hydrophilic, zwiterionic characteristics. In the present.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.