Reversal of p-glycoprotein-mediated multidrug resistance by gp

• At: 2008 FIP Congress in Basel (Switzerland)
• Type: Poster
• By: XU, Hongbin (The Tenth People’s Hospital affiliated to Tongji University, Shanghai, China)
• Co-author(s): Li, Ling (The Tenth People’s Hospital affiliated to Tongji University, SHANGHAI, China)
  
• Abstract:

  Aim:Multidrug resistance(MDR) has been a major problem in cancer chemotherapy.Many factors contribute to the happening of MDR.The development of P-glycoprotein (P-gp) inhibitor could be effective to MDR.The aim of this study was to observe the effects of GP,an ginkgo polyprenol, on the inhibition of P-gp function and P-gp-mediated MDR in K562/DOX..

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