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Enhancement of transbuccal permeation of buspirone by hydroxypropyl-ß-cyclodextrin: formulation and in vitro evaluation

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Poster
  • By: VENKATASIMHADRI NAIDU, Kalamata (University College of Pharmaceutical Sciences, Kakatiya University, Warangal (a.p)-506009, India)
  • Co-author(s): Eaga, Chandra Mohan (University College of Pharmaceutical Sciences, Kakatiya University, WARANGAL (A.P)-506009, India)
    Bandari, Suresh (University College of Pharmaceutical Sciences, Kakatiya University, WARANGAL (A.P)-506009, India)
    Meka, Lingam (University College of Pharmaceutical Sciences, Kakatiya University, WARANGAL (A.P)-506009, India)
    Yamsani, Madhusudan Rao (University College of Pharmaceutical Sciences, Kakatiya University, WARANGAL (A.P)-506009, India)
  • Abstract:

    The buccal mucosa providing direct entry into the systemic circulation appears to be a potential site for the delivery of buspirone. In order to achieve a sufficient buccal bioavailability a drug delivery system with permeation enhancing and mucoadhesive properties is needed. In the first part of the study, the enhancing effect of..

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Last update 4 October 2019

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