Investigation of stability and pharmacokinetics of a interleukin-2 liposome formulation for pulmonary administration
- At: 2008 FIP Congress in Basel (Switzerland)
- Type: Poster
- By: ÇELEBI, Nevin (Gazi University Faculty of Pharmacy Department of Pharmaceutical Technology, Ankara, Turkey)
- Co-author(s): Çilek, Ayse (Gazi University Faculty of Pharmacy Department of Pharmaceutical Technology, ANKARA, Turkey)
Yücel, Aysegül (Gazi University School of Medicine Department of Immunology, Ankara, Turkey)
Akbulut, Gonca (Gazi University School of Medicine Department of Physiology, Ankara, Turkey)
The objective of this study was to prepare a stable liposome formulation of interleukin-2 (IL-2). Another objective is to examine the effects of pulmonary administration of IL-2 liposome and solution dosage form on plasma IL-2 levels in rats. The pharmacokinetics and bioavailability parameters were also calculated. The stability of the liposome .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.