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DESIGN OF NOVEL STEROID RECEPTOR CO-ACTIVATOR (SRC) MODULATORS FOR MALIGNANT DISEASE MANAGEMENT

  • At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
  • Type: Poster
  • By: SHOEMAKE, Claire (University of Malta, Pharmacy, Malta)
  • Co-author(s): Ruth Fiorentino: Pharmacy, University of Malta, Msida, Malta
    Claire Shoemake: Pharmacy, University of Malta, Msida, Malta
  • Abstract:

    Background

    The Steroid Receptor Co-activator (SRC) is overexpressed in several cancer types. There is the consequent expectation that SRC antagonists would mitigate tumour growth. The study by Wang et al. showed paradoxically that SRC overstimulation disrupts tumour homeostasis and proposed experimental molecule MCB-613 as an effective agonist with ..

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Last update 13 May 2019

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