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DESIGN OF NOVEL STEROID RECEPTOR CO-ACTIVATOR (SRC) MODULATORS FOR MALIGNANT DISEASE MANAGEMENT

  • At: AbuDhabi (United Arab Emirates) (2019)
  • Type: Poster
  • Poster code: POS-DDD-007
  • By: SHOEMAKE, Claire (University of Malta, Pharmacy, Malta)
  • Co-author(s): Ruth Fiorentino: Pharmacy, University of Malta, Msida, Malta
    Claire Shoemake: Pharmacy, University of Malta, Msida, Malta
  • Abstract:

    Background

    The Steroid Receptor Co-activator (SRC) is overexpressed in several cancer types. There is the consequent expectation that SRC antagonists would mitigate tumour growth. The study by Wang et al. showed paradoxically that SRC overstimulation disrupts tumour homeostasis and proposed experimental molecule MCB-613 as an effective agonist with ..

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Last update 28 September 2023

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