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Development of coated nifedipine-loaded gelatin microcapsule as a long acting oral delivery with enhanced bioavailability

  • In: Industrial Pharmacy - Posters
  • At: Basel (Switzerland) (2008)
  • Type: Poster
  • Poster code: IPS-P-028
  • By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, South-Korea)
  • Co-author(s): Li, Dong Xun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Yoo, Dong Sung (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Sung, Jun Ho (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Kim, Jung-Ae (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Woo, Jong Soo (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Lee, Young-Im (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Lee, Won Mo (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Yoo, Bong Kyu (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Koo, Yoon Bon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Choi, Han-Gon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  • Abstract:

    To develop the long acting nifedipine oral delivery system with enhanced bioavailability, gelatin microcapsule containing nifedipine dissolved in ethanol in gelatin shell was prepared using a spray-dryer, and then coated microcapsule was obtained by coating the gelatin microcapsule with Eudragit acrylic resin. The dissolution test and..

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Last update 28 September 2023

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