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Characterization and evaluation of solid dispersions of valsartan prepared with gelatin and hpmc2910

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Poster
  • By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, South-Korea)
  • Co-author(s): Li, Dong Xun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Sung, Jun Ho (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Woo, Jong Soo (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Lee, Jong Suk (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Im, Jong Seub (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Rhee, Jong-Dal (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Hong, Myung-Ja (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Lee, Young-Im (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
    Choi, Han-Gon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  • Abstract:

    Solid dispersions prepared with gelatin and HPMC2910 as a carrier were investigated for improving the dissolution and bioavailability of valsartan, a poorly water-soluble compound. The solid dispersions with various ratios of gelatin to HPMC2910 were obtained by spray drying method. They were characterized using differential scanning calorimetry..

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Last update 4 October 2019

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