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Synthesis and antitumor activity of 2-substituted benzimiazoles
- At: Basel (Switzerland) (2008)
- Type: Poster
- By: Y. ELBAYAA, Rasha (Faculty of Pharmacy, Alexandria, Egypt)
- Co-author(s): M. Youssef, Amal (Faculty of Pharmacy, ALEXANDRIA, Egypt)
H. Badr, Mona (Faculty of Pharmacy, ALEXANDRIA, Egypt) - Abstract:
Benzimidazole derivatives are of wide interest because of their diverse biological activity and clinical applications. Pyrrolo[1,2-a]benzimidazoles represent a new class of antitumor agents exhibiting cytotoxic activity against a variety of cancer cell lines. The mechanism of cytotoxicity involves reductive alkylation of DNA accompanied by..
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Last update 4 October 2019