Synthesis and antitumor activity of 2-substituted benzimiazoles
- At: 2008 FIP Congress in Basel (Switzerland)
- Type: Poster
- By: Y. ELBAYAA, Rasha (Faculty of Pharmacy, Alexandria, Egypt)
- Co-author(s): M. Youssef, Amal (Faculty of Pharmacy, ALEXANDRIA, Egypt)
H. Badr, Mona (Faculty of Pharmacy, ALEXANDRIA, Egypt)
Benzimidazole derivatives are of wide interest because of their diverse biological activity and clinical applications. Pyrrolo[1,2-a]benzimidazoles represent a new class of antitumor agents exhibiting cytotoxic activity against a variety of cancer cell lines. The mechanism of cytotoxicity involves reductive alkylation of DNA accompanied by.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.