Berberine prevents tnf-?-induced inflammatory response in human umbilical vein endothelial cells

• At: 2008 FIP Congress in Basel (Switzerland)
• Type: Poster
• By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, South-Korea)
• Co-author(s): Lee, Jong Suk (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Park, Su-Young (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Kim, Ah Ra (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Kim, Kyoung-Jin (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Choi, Mi Kyoung (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  Kim, Jung-Ae (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, GYEONGSANGBUK-DO, South-Korea)
  
• Abstract:

  Berberine is known to exert cardio-protective and anti-proliferative actions in vascular smooth muscle cells. Vascular inflammation has been implicated in the progression of cardiovascular diseases such as atherosclerosis. In the present study, we found that berberine concentration-dependently inhibited tumor necrosis factor-? (TNF-?)-induced..

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