Menu
  • Join
  • Login
  • Contact
 

Search abstracts


Effects of esomeprazole and vonoprazan on the disposition of proguanil.

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: ITO, Kiyomi (Musashino University)
  • Co-author(s): Ryohkan Funakoshi: Graduate School of Pharmaceutical Sciences, Musashino University, Tokyo, Japan;Pharmacy Administration, Kameda Medical Center, Chiba,
    Yukana Tomoda: Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan
    Toshiyuki Kudo: Graduate School of Pharmaceutical Sciences, Musashino University, Tokyo, Japan
    Yoshiaki Yamagishi: Graduate School of Pharmaceutical Sciences, Musashino University, Tokyo, Japan
    Kosho Makino: Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan
    Hideyo Takahashi: Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan
    Kenichi Furihata: P-One Clinic, Keikokai Medical Corporation, Tokyo, Japan
    Hiroyuki Kusuhara: Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan
    Kiyomi Ito: Graduate School of Pharmaceutical Sciences, Musashino University, Tokyo, Japan
  • Abstract:

    Background

    In vitro inhibitory effect of vonoprazan, a proton pump inhibitor, on CYP2C19 activity is much weaker than that of esomeprazole at their clinically relevant concentrations. However, in a recent clinical study, vonoprazan showed a more potent inhibition compared with esomeprazole against the antiplatelet function of clopidogrel which is..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 13 May 2019

FIP Congresses