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Matrine attenuates nonalcoholic fatty liver diseases through inhibition serca2c

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: ZHANG, Yan (Tangdu Hospital, Fourth Military Medical Universit, Department of Pharmacy,)
  • Co-author(s): Yan Zhang
    Lei Shi: Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, xi'an, China
    Song Zhang: Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
    Shun Guo: Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
    Xiaobo Gao: Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
  • Abstract:

    Background

    The histological spectrum of nonalcoholic fatty liver diseases (NAFLD) ranges from hepatic steatosis to steatohepatitis. Redistribution of intracellular calcium from the endoplasmic reticulum (ER) to the mitochondria can lead to ER stress, induce mitochondrial dysfunction, and accelerate the development of NAFLD to steatohepatitis

    Methods

    H

    ..

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Last update 13 May 2019

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