Inhibition of scutellaria baicalensis on senescence-associated secretory phenotype production

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: LIM, Hyun (College of pharmacy, Kangwon National University)
  • Co-author(s): Hyun Lim: College of Pharmacy, Kangwon National University, Chuncheon, Korea, Republic Of
    Ki Sun Kwon: College of Pharmacy, Kangwon National University, Chuncheon, Korea, Republic Of
    Yong Soo Kwon: College of Pharmacy, Kangwon National University, Chuncheon, Korea, Republic Of
    Hyun Pyo Kim: College of Pharmacy, Kangwon National University, Chuncheon, Korea, Republic Of
  • Abstract:

    Background

    As cells age, continuous exposure to senescence-associated secretory phenotype (SASP) from adjacent cells acts as chronic low-grade inflammation, leading to many chronic degenerative diseases. 

    Methods

    The ethanol extract and 17 flavonoid constituents from Scutellaria root were incubated for 6 days after treatment with bleomycin for 24 h

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