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Gastric retention: an approach to enhance bioavailability of norfloxacin

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Poster
  • By: MAIR, Parth (Sinhgad College Of Pharmacy,Pune, India, Pune, India)
  • Co-author(s): Kulkarni, Nilesh (Sinhgad College Of Pharmacy,Pune, India, PUNE, India)
    Ranpise, Nisharani (Sinhgad College Of Pharmacy,Pune, India, PUNE, India)
    Gaikwad, Madhuri (R.C. Patel College of Pharmacy, Shirpur, India)
  • Abstract:

    Present study deals with an attempt to improve bioavailability of norfloxacin, which has very low bioavailability of 30%. Although it undergoes very low first pass metabolism, the rate at which the drug is absorbed is also slow. Furthermore, norfloxacin has solubility at pH lower than 5 and pH higher than 10. Thus an attempt was made to increase..

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Last update 4 October 2019

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