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Prediction of sirna delivery using topological descriptors and artificial neural network

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Poster
  • By: PIRIYAPRASARTH, Suchada (Faculty of Pharmacy, Silpakorn University, Nakhon-pathom, Thailand)
  • Co-author(s): Techaarpornkul, Sunee (Faculty of Pharmacy, Silpakorn University, NAKHON-PATHOM, Thailand)
    Opanasopit, Praneet (Faculty of Pharmacy, Silpakorn University, NAKHON-PATHOM, Thailand)
    Nunthanid, Jurairat (Faculty of Pharmacy, Silpakorn University, NAKHON-PATHOM, Thailand)
  • Abstract:

    Introduction: Delivery of siRNA into cells is a key step for efficient gene silencing. Chitosan is one of a safe and cost-effective siRNA delivery system. Experimentally measurement of a variety of chitosan-siRNA complexes for siRNA transport into cells, is expensive and time consuming. To analyze the relationship between molecular properties and..

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Last update 4 October 2019

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