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Optimization of derivatization procedure for determination of succinic acid

  • At: Glasgow (Scotland) (2018)
  • Type: Poster
  • Poster code: POS-ASP-005
  • By: JARUKAS, Laurynas (Lithuanian University of Health Sciences, Faculty of Pharmacy, Department of Analytical and Toxicological Chemistry)
  • Co-author(s): Laurynas Jarukas
    Justina Kamarauskaitė: Department of Pharmacognosy, Lithuanian University of Health Sciences, Faculty of Pharmacy, Kaunas, Lithuania
    Mindaugas Marksa: Department of Analytical and Toxicological Chemistry, Lithuanian University of Health Sciences, Faculty of Pharmacy, Kaunas, Lithuania
    Rasa Banienė: Neuroscience Institute, Lithuanian University of Health Sciences, Kaunas, Lithuania
    Sonata Trumbeckaitė: Department of Pharmacognosy, Lithuanian University of Health Sciences, Faculty of Pharmacy, Kaunas, Lithuania
    Liudas Ivanauskas: Department of Analytical and Toxicological Chemistry, Lithuanian University of Health Sciences, Faculty of Pharmacy, Kaunas, Lithuania
  • Abstract:

    Background

    It is well known that ischemia/reperfusion injury induces cellular damage, which is accompanied by a variety of metabolic alterations. Several studies indicate that accumulation of mitochondrial metabolite succinate (citric acid cycle intermediate) during ischemia controls reperfusion injury through mitochondrial reactive oxygen..

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Last update 28 September 2023

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