Histaminergic mechanisms and electroshock seizures: some drug interactions in mice

• In: SIG: Medicinal Chemistry - Posters
• At: Basel (Switzerland) (2008)
• Type: Poster
• Poster code: MC-P-001
• By: VOHORA, Divya (Jamia Hamdard, New Delhi, New Delhi, India)
• Co-author(s): Devi, P. Uma (Jamia Hamdard, New Delhi, NEW DELHI, India)
  Manocha, Anshu (Jamia Hamdard, New Delhi, NEW DELHI, India)
  
• Abstract:

  Several lines of evidence, both experimental and clinical, have indicated an anticonvulsant action of endogenous histamine. N-acetylcysteine, an antioxidant, is reported to enhance the release of histamine from mast cells. We have earlier reported additive/ synergistic effects of antioxidant drug (NAC) with antiepileptic drugs phenytoin (PHT) and..

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