Formulation and evaluation of phh-dependent drug delivery system of lercanidipine hydrochloride

• In: Industrial Pharmacy - Posters
• At: Basel (Switzerland) (2008)
• Type: Poster
• Poster code: IPS-P-005
• By: DR.T.M.PRAMOD KUMAR, Dr.T.M.PRAMOD KUMAR (J.S.S.COLLEGE OF PHARMACY, S.S.NAGAR, MYSORE, KARNATAKA, INDIA, Mysore, India)
• Co-author(s): Balamuralidhara V., Balamuralidhara V. (J.S.S.COLLEGE OF PHARMACY, S.S.NAGAR, MYSORE, KARNATAKA, INDIA, MYSORE, India)
  Dr.H.G.SHIVAKUMAR, Dr.H.G.SHIVAKUMAR (J.S.S.COLLEGE OF PHARMACY, S.S.NAGAR, MYSORE, KARNATAKA, INDIA, MYSORE, India)
  
• Abstract:

  A pH-dependent drug delivery system was developed by using three kinds of pH-dependent polymers. Lercanidipine HCl, a dihydropyridine calcium antagonist, was selected as it is poorly water soluble drug. To improve its dissolution rate, pH-dependent drug delivery system for lercanidipine HCl having a solid dispersed matrix structure was developed...

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