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Hla variants involved in drug hypersensitivity reactions

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: HOLSAPPEL, Inge (Royal Dutch Pharmacists Association, Medicine Information Centre, Den Haag, Netherlands)
  • Co-author(s): Inge Holsappel: Medicine Information Centre, Royal Dutch Pharmacists Association, Den Haag, Netherlands
    Ka-Chun Cheung: Medicine Information Centre, Royal Dutch Pharmacists Association, Den Haag, Netherlands
    Mandy Crommentuijn-van Rhenen: Medicine Information Centre, Royal Dutch Pharmacists Association, Den Haag, Netherlands
    Marga Nijenhuis: Medicine Information Centre, Royal Dutch Pharmacists Association, Den Haag, Netherlands
  • Abstract:

    Background

    Human Leukocyte Antigen (HLA) has an essential role in the immune system. These proteins bind peptides in the cell and present them on the surface of the cells so the immune system is activated when abnormal peptides are presented. Genetic variation in HLA can lead to differences in peptides they can bind and therefore determine the..

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Last update 4 October 2019

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