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Screening of oxidative metabolism of flavonoid aglycones by liquid chromatography-mass spectrometry

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: BENKOVIC, Goran (Agency for Medicinal Products and Medical Devices, Zagreb, Croatia)
  • Co-author(s): Goran Benković: Official Medicines Control Laboratory, Agency for Medicinal Products and Medical Devices, Zagreb, Croatia
    Rajka Truban Žulj: Official Medicines Control Laboratory, Agency for Medicinal Products and Medical Devices, Zagreb, Croatia
    Mirza Bojić: Department for Pharmaceutical Chemistry, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, Croatia
  • Abstract:

    Background

    Cytochromes P450 are the most significant enzymes for drug metabolism. Flavonoids are common constituents of everyday diet that have been shown to have beneficial potential on human health. Flavonoids undergo substantial hepatic metabolism and the metabolites might significantly contribute to the effects of these dietary constituents as

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Last update 4 October 2019

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