Benzo[a]carbazoles inhibitors of 4t1 malignant cells growth

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: MARTIARENA, Jorge (School of Pharmacy, Biological Chemistry, Buenos Aires, Argentina)
  • Co-author(s): Jorge Luis Martiarena:
    Maximiliano Reybet: Biological Chemistry, School of Pharmacy, Buenos Aires, Argentina
    Diego Cóbice: Metabolomics and Proteomics Clinical Biochemistry and Molecular Analyses, Ulster University, Belfast, Ireland
  • Abstract:

    Background

     The antibacterial and antiangiogenic activity of benzo[a]carbazoles derivatives (C1 y G1) were shown previously. Currently, new drugs that bind different targets are becoming a new trend in Drug Discovery.

    Purpose

    To assess benzo[a]dihydrocarbazole G1 derivative as 4T1 malignant cells growth inhibitor.

    Methods

    G1 was synthesized starting..

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