Simultaneous analysis of liposomal nanoparticle and released drug using hplc

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: KATO, Masaru (The University of Tokyo, Tokyo, Japan)
  • Co-author(s): Masaru Kato
  • Abstract:

    Methods

    The influence of surrounding environment (pH, temperature, and organic modifier) on release of doxorubicin from DOXIL was investigated.

    Results

    It was found that temperature above the phase transition temperature, basic condition, and membrane permeable base, such as Tris, are effected on the doxorubicin..

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