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Potential interaction of scutellariae radix on the pharmacokinetics and pharmacodynamics of metformin in rats

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: CHOI, Young Hee (Dongguk University, College of Pharmacy, Korea, Republic Of)
  • Co-author(s): Young Hee Choi: College of Pharmacy, Dongguk University, Korea, Republic Of
    Byung Hoon You: College of Pharmacy, Dongguk University, Korea, Republic Of
    Young-Won Chin: College of Pharmacy, Dongguk University, Korea, Republic Of
  • Abstract:

    Background

    Formerly metformin and Scutellariae Radix extract combination has been reported to enhance anti-diabetic activity.  Organic cation transporters and multi-drug and toxin extrusion proteins in liver and kidney are determinant factors on hepatic distribution and renal clearance of metformin.

    Purpose

    To predict the potential of interaction..

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Last update 4 October 2019

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