Development and evaluation of lyophilized orally disintegrating tablets containing metformin hydrochloride and glyburide

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: AKDAG CAYLI, Yagmur (Hacettepe University, Pharmaceutical Technology, Turkey)
  • Co-author(s): Yagmur Akdag Cayli:
    Tugba Gulsun: Pharmaceutical Technology, Hacettepe University, Ankara, Turkey
    Nihan Izat: Pharmaceutical Technology, Hacettepe University, Ankara, Turkey
    Meltem Cetin: Pharmaceutical Technology, Atatürk University, Erzurum, Turkey
    Levent Oner: Pharmaceutical Technology, Hacettepe University, Ankara, Turkey
    Selma Sahin: Pharmaceutical Technology, Hacettepe University, Ankara, Turkey
  • Abstract:

    Background

    Metformin hydrochloride (MH) and glyburide (GB) are oral antidiabetic agents which can be combined to treat Type 2 diabetes. To our knowledge, there is no commercially available orally disintegrating tablets (ODTs) for this combination.

    Purpose

    The aim of this study was to develop and evaluate MH and GB containing ODT by freeze-drying..

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