Development and validation method for quantitative determination of rifampicin in human plasma and its application in bioequivalence test

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: LUKITANINGSIH, Endang (Gadjah Mada University, Pharmaceutical Chemistry Department, Yogyakarta, Indonesia)
  • Co-author(s): Endang Lukitaningsih:
    Fathul Jannah: Advanced Pharmaceutical Sciences lab, Gadjah Mada University, Yogyakarta, Indonesia
    Arief Rahman Hakim: Pharmacology and Clinical Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia
    Ratna Dewi Puspita: Gadjah Mada University Hospital, Gadjah Mada University, Yogyakarta, Indonesia
    Zullies Ikawati: Pharmacology and Clinical Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia
  • Abstract:

    Background

    Rifampicin has been used worldwide as first line drug-prescribed throughout tuberculosis therapy

    Purpose

    This study aims to develop and to validate an HPLC method couple with a UV detection for determination of rifampicin for bioequivalence study.

    Methods

    The chromatographic separation was achieved on a RP-C18 column (LachromHitachi, 250 x..

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