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A comprehensive pharmacokinetic modeling of aceclofenac metabolism to major metabolites in healthy volunteers
- At: 2017 FIP Congress in Seoul (South Korea)
- Type: Poster
- By: KIM, Eunyoung (Chungang University, Department of Health, Social and Clinical Pharmacy, College of Pharmacy, Seoul, Korea, Republic Of)
- Co-author(s): Eunyoung Kim: Department of Health, Social and Clinical Pharmacy, College of Pharmacy, Chungang University, Seoul, Korea, Republic Of
Wonku Kang: College of Pharmacy, Chungang University, Seoul, Korea, Republic Of
BackgroundAceclofenac has been used widely as a potent analgesic and anti-inflammatory drug. Aceclofenac is converted to its major metabolites via CYP2C9-mediated hydroxylation and hydrolysis.
PurposeThe main purpose of this study was to develop a pharmacokinetic model reflecting the metabolic pathway of aceclofenac using a compartmental modeling.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.
Last update 4 October 2019