Pharmacokinetics of doxorubicin encapsulated long circulating lipid nanospheres
- At: 2004 FIP Congress in New Orleans (USA)
- Type: Poster
- By: VEERAREDDY, Prabhakar Reddy (Kakatiya University, Univ. College of Pharm Sci., Warangal, India)
- Co-author(s): Patlolla, Ram Reddy (Kakatiya University, WARANGAL, India)
Jannapally (Kakatiya University, WARANGAL, India)
Vobalaboina, Venkateswarlu (Kakatiya University, WARANGAL, India)
Doxorubicin lipid nanospheres (LND) and long circulating lipid nanospheres (PEG-LND) were prepared by ion pairing of doxorubicin hydrochloride with dicetyl phosphate at a molar ratio of 1:2. The pharmacokinetics of LND and PEG-LND were compared to the doxorubicin solution (Dox-S). The same dose of each formulation (7.5 mg/kg) of doxorubicin was.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.