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Pharmacokinetics of doxorubicin encapsulated long circulating lipid nanospheres

  • At: 2004 FIP Congress in New Orleans (USA)
  • Type: Poster
  • By: VEERAREDDY, Prabhakar Reddy (Kakatiya University, Univ. College of Pharm Sci., Warangal, India)
  • Co-author(s): Patlolla, Ram Reddy (Kakatiya University, WARANGAL, India)
    Jannapally (Kakatiya University, WARANGAL, India)
    Vobalaboina, Venkateswarlu (Kakatiya University, WARANGAL, India)
  • Abstract:

    Doxorubicin lipid nanospheres (LND) and long circulating lipid nanospheres (PEG-LND) were prepared by ion pairing of doxorubicin hydrochloride with dicetyl phosphate at a molar ratio of 1:2. The pharmacokinetics of LND and PEG-LND were compared to the doxorubicin solution (Dox-S). The same dose of each formulation (7.5 mg/kg) of doxorubicin was..

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Last update 4 October 2019

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