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Solubilisation of ibuprofen in mixed-surfactant systems containing poloxamer 407 and selected polioxyethylene-derivative surfactants

  • In: Poster presentation
  • At: Seoul (South Korea) (2017)
  • Type: Poster
  • Poster code: POS-FDP-024
  • By: PLUTA, Janusz (Polish Pharmaceutical Society, Department of Drug Form Technology, Warsaw, Poland)
  • Co-author(s): Janusz Pluta: Department of Drug Form Technology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland;Department of Pharmacology, Opole Medical School (PMWSZ), Opole, Poland
    Kamil P Grela: Department of Drug Form Technology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland
    Dominik M Marciniak: Department of Drug Form Technology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland
    Anna Cap:
    Jakub Burak: Department of Drug Form Technology, Faculty of Pharmacy, Wroclaw Medical University, Wrocław, Poland
  • Abstract:

    Background

    The nonionic surfactant poloxamer 407 (P407) is known as a gel-forming excipient, but also as an efficient solubiliser for some lipophilic substances.

    Purpose

    The aim of this study was to measure the influence of chosen polyoxyethylene-derivative surfactants (PEX) on the solubility of ibuprofen (IBU) in thermogelling P407 solutions at..

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Last update 28 September 2023

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