Surface modification of solid lipid nanoparticles for oral delivery of curcumin: improvement of bioavailability through enhanced cellular uptake, and lymphatic uptake

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: CHO, Cheong-Weon (Korea, Republic Of)
  • Co-author(s): Young-Guk Na
    Jong-Suep Baek
    Cheong-Weon Cho
  • Abstract:

    Background

    Curcumin has been reported to exhibit potent anticancer effects. However, poor solubility, bioavailability and stability of curcumin limit its in vivo efficacy for the cancer treatment. 

    Purpose

    The first objective of this study was to fabricate NCC-SLN for preventing burst release of curcumin in simulated gastric fluid and to evaluate..

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