Polypeptide nanovehicle co-encapsulating doxorubicin and quercetin for a synergistic combination to enhance chemotherapeutic activity in solid tumors

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: YONG, Chul Soon (Yeungnam University, Gyeongsan-Si, Korea, Republic Of)
  • Co-author(s): Woo Hyun Shin: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Hima Bindu Ruttala: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Phung Cao Dai: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Myung-Ja Hong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jee-Heon Jeong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Dong Shik Kim: Hanyang University, Ansan-si, Korea, Republic Of
    Han-Gon Choi: Hanyang University, Ansan-si, Korea, Republic Of
    Chul Soon Yong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jong Oh Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  • Abstract:

    Background

    In this study, we report a facile method to construct bioactive and biodegradable polypeptide nanovehicles as an advanced platform technology for application in cancer therapy.

    Purpose

    We have synthesized a bioactive (poly(phenylalanine)-b-poly(L-histidine)-b-poly(ethylene glycol) polypeptide nanoconstruct to co-load doxorubicin (DOX) and..

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