Zein nanoparticles loaded with vorinostat and bortezomib combination for synergistic anticancer effects in metastatic prostate cancers

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: YONG, Chul Soon (Yeungnam University, Gyeongsan-Si, Korea, Republic Of)
  • Co-author(s): Jong Seong Lee: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Raj Kumar Thapa: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Hanh Thuy Nguyen: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Min Hyun Sung: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jee-Heon Jeong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Dong Shik Kim: Hanyang University, Ansan-si, Korea, Republic Of
    Han-Gon Choi: Hanyang University, Ansan-si, Korea, Republic Of
    Chul Soon Yong: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Jong Oh Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  • Abstract:

    Background

    Prostate cancer is a leading cause of cancer-related death among men owing to its ability to develop drug resistance and subsequent metastasis. Hence, nanoparticle-based combination chemotherapeutics could be a viable treatment strategy.

    Purpose

    We aimed to prepare vorinostat (Vor) and bortezomib (Bor) combination-loaded zein nanoparticles ..

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