Cd9-targeted delivery of rapamycin for anti-senescence activity in human dermal fibroblasts

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: YONG, Chul Soon (Yeungnam University, Gyeongsan-Si, Korea, Republic Of)
  • Co-author(s): Jong Seong Lee: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Hanh Thuy Nguyen: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Raj Kumar Thapa: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Zar Chi Soe: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
    Dong Shik Kim: Hanyang University, Ansan-si, Korea, Republic Of
    Han Gon Choi: Hanyang University, Ansan-si, Korea, Republic Of
    Chul Soon Yong:
    Jong Oh Kim: Yeungnam University, Gyeongsan-Si, Korea, Republic Of
  • Abstract:

    Background

    Premature cellular senescence refers to the state of irreversible cell cycle arrest due to DNA damage or other stresses. CD9 is a member of the tetraspanins family with four transmembrane domains. In recent years, the overexpression of CD9 has been linked to the development of cancer tissues and cellular senescence.

    Purpose

    CD9 monoclonal..

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