Development of linagliptin ph sensitive polymeric nanoparticles using quality by design approach for the treatment of diabetes mellitus

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Poster
  • By: VENI, D. Krishna (JSS College of Pharmacy, Pharmaceutics, Mysuru, India)
  • Co-author(s): D. Krishna Veni
    N. Vishal Gupta
  • Abstract:

    Background

    Linagliptin is a DPP-4 Inhibitor used in the treatment of Type II Diabetes. One of the major drawbacks of this drug was found to be degradation in a gastric environment which lead to low bioavailability. In this study to overcome this challenge i have developed a new drug delivery and formulated as Polymeric Nanoparticles (PNP’s) to..

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